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A Scalable Platform with Structural Advantage

Unlike genomics-only approaches, which predict response based on mutation patterns, fScreen directly measures drug efficacy in real patient cells. Built on standardized high-throughput flow cytometry and integrated analytics software, fResolve, the platform is engineered to enable:

Transforming Cancer Treatment with Functional Precision

exalt® is building the next generation of precision oncology—moving beyond genomic probability toward direct, functional measurement of treatment response.

Our proprietary platform, fScreen, is testing how a patient’s living tumor cells respond to more than 100 approved cancer drugs at single-cell resolution. Within 72 hours, oncologists will receive a ranked, actionable treatment profile—enabling evidence-based therapy selection tailored to the individual patient.

 

In clinical studies, fScreen-guided therapy has demonstrated significantly improved response rates in late-stage hematologic cancers, validating the power of functional precision medicine.

​The right Drug.
For the right Patient.
At the right Time.

Our Vision

exalt® aims to make functional precision diagnostics the global standard of care—reducing ineffective treatments, improving patient outcomes, and unlocking a new data-driven era of oncology.

News

24 October 2025

EIT x exalt

European Institute for Innovation and Technology (EIT) MedTech by European Commission awards exalt of the 10 finalists as best European MedTech Start-up in 2025

24 June 2025

Women TechEU x exalt

exalt is selected as Winner of the Women-led tech start-up bootcamp in 2025 

24 April 2025

EXALT-2 Clinical Trial - feasibility analysis

Comparing functional and genomic-based precision medicine in blood cancer patients

Hemasphere 24 April 2025

Lukas Kazianka, Alexander Pichler, ..., Tea Pemovska et Philipp Staber

15 February 2024 

Nature biotechnology

Staber and his team are now recruiting patients into a second prospective study in patients with hematological cancer, EXALT-2, which is comparing the utility of genomic screening, single-cell functional precision medicine and physicians’ choice in guiding therapy selection. 

14 February 2024​

Nature feature

All eyes are therefore on Staber and his randomized trial, which researchers anticipate will go a long way towards convincing clinicians that genomics is not the be-all and end-all of personalized care. "Paradigm shifts ... . 

23 November 2023

Pre-Seed  AWS Deeptech

exalt receives support by the Austrian Promotional Bank Deep Tech Pre-Seed.

more

9 November 2022

Falling Walls Berlin

exalt was invited for the Start-up pitch at the Falling Walls Sciencepreneurs Night 

8 September 2022 

European Forum Alpbach

exalt was voted as best deep tech start-up​​

1 September 2022

Hermann Hauser Business School Tyrol / Cambridge cluster

Best Tech-Start up prize in 2022. exalt was supported by the LBI Innovator's road program (Ludwig Boltzmann

1 February 2022 

EXALT-1 Clinical Trial

Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

Clinical trials

NCT03096821
Comprehensive Genomic Profiling and Next Generation Functional Drug Screening for Patients With Aggressive Haematological Malignancies (EXALT-2)

EXALT-2 Clinical Trial

recruiting

NCT03096821
Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

EXALT-1 Clinical Trial

completed

Publications

EXALT-2 Clinical Trial - feasibility analysis

Comparing functional and genomic-based precision medicine in blood cancer patients

Hemasphere 24 April 2025

Lukas Kazianka, Alexander Pichler, ..., Tea Pemovska et Philipp Staber

Read More

EXALT-1 Clinical Trial

Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders
Cancer Discovery
1 February 2022 

Christoph Kornauth, Tea Pemovska, Gregory I. Vladimer, ..., Giulio Superti-Furga; Berend Snijder et Philipp B. Staber

Read More

Team

Tea Pemovska full pictur_lighter.jpg
Tea Pemovska, PhD
CSO
co-founder
  • LinkedIn
staber_gabriela_104110_300.jpg
Gabriela Staber, Dr. iur LLM
Legal
co-founder
  • LinkedIn
portrait_Alexander_edited.jpg
Alexander Pichler, MD
CEO
co-founder
  • LinkedIn
portrait_Philipp Staber_edited_edited.png
Philipp Staber, MD PhD
co-CEO
co-founder
  • LinkedIn
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